Effective screen for amyloid β aggregation inhibitor using amyloid β-conjugated gold nanoparticles
نویسندگان
چکیده
منابع مشابه
Effective screen for amyloid β aggregation inhibitor using amyloid β-conjugated gold nanoparticles
The abnormal aggregation of amyloid β (Aβ) and its subsequent intra- and extracellular accumulation constitute the disease-causing cascade of Alzheimer's disease (AD). The detection of Aβ aggregates and senile plaque formation, however, is nearly impossible during early pathogenesis, and the absence of a convenient screen to validate the activity of Aβ aggregation regulators impedes the develop...
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iii ACKNOWLEDGEMENTS I would like to acknowledge my advisor and mentor Dr. Moss for all of her patience, help, and understanding throughout the years. I would like to thank my committee members Dr. Blanchette, Dr. Shazly, and Dr. Price for their help and input in preparing my dissertation. I would also like to thank all of the previous and current members of Dr. Moss' lab for all their help. I ...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2010
ISSN: 1178-2013
DOI: 10.2147/ijn.s15278